Abstract
DEPLETION of ascorbic acid from the ovary of the immature rat rendered pseudopregnant by treatment with pregnant mare's serum (PMS) and human chorionic gonadotrophin (HCG) is used as an assay for luteinizing hormone (LH). A significant diurnal variation in the ovarian ascorbic acid (OAA) content was observed by Stevens1 in such rats. These variations may be important in the assay of LH by Parlow's method.
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References
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DE LA LASTRA, M., CROXATTO, H. Diurnal Variations in Ovarian Ascorbic Acid Content of Pseudopregnant Immature Rats used in Parlow's Test. Nature 208, 789–790 (1965). https://doi.org/10.1038/208789a0
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DOI: https://doi.org/10.1038/208789a0
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