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‘Lipid A’ Component from the Cell-walls of Pseudomonas aeruginosa

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Abstract

CONSIDERABLE attention1 has been paid to the lipopolysaccharide complexes which are found in the cell walls of Gram-negative bacteria. The extraction of whole cells or of isolated cell walls with aqueous phenol provides these lipopolysaecharides. The lipopolysaccharide component may be hydrolysed by dilute acid to give ‘lipid A’ and sugar. Nowotny2 has suggested the following structure for the ‘lipid A’ derived from some strains of Salmonella. , F, fatty acid; GA, D-glucosamine; P, phosphoric acid.

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References

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CLARKE, K., GRAY, G. & REAVELEY, D. ‘Lipid A’ Component from the Cell-walls of Pseudomonas aeruginosa. Nature 208, 586–587 (1965). https://doi.org/10.1038/208586a0

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