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Tumour-promoting Agents in Unburned Cigarette Tobacco

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Abstract

UNBURNED American cigarette tobacco is an excellent source of tumour-promoting agents1. The aqueous extract from as little as one-half cigarette per day is sufficient to produce skin tumours in mice painted previously with 125 µg of 7,12-dimethylbenz[α]anthracene (DMBA). The work recorded here gives further information about the properties of the active substance.

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BOCK, F., SHAMBERGER, R. & MYERS, H. Tumour-promoting Agents in Unburned Cigarette Tobacco. Nature 208, 584–585 (1965). https://doi.org/10.1038/208584a0

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