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Anti-arrhythmic Action of Bretylium

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Abstract

THE anti-arrhythmic action of guanethidine which was found to prevent a type of clinical paroxysmal ventricular tachycardia1 and prevented experimental atrial fibrillation2 suggested that other agents which interfere with the release of catecholamines might exhibit similar effectiveness.

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References

  1. Harris, W. E., Semler, H. J., and Griswold, H. E., Amer. Heart J., 67, 812 (1964).

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  2. Leveque, P. E., Nature, 203, 1389 (1964).

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  3. Leveque, P. E., Arch. Intern. Pharmacodyn., 149, 279 (1964).

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  4. Boura, A. L. A., and Green, A. F., Brit. J. Pharmacol., 14, 536 (1959).

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  5. Boura, A. L. A., et al., Brit. J. Pharmacol., 15, 256 (1960).

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Authors and Affiliations

  1. Department of Pharmacology, Ohio State University, Columbus

    PHILLIP E. LEVEQUE

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  1. PHILLIP E. LEVEQUE
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LEVEQUE, P. Anti-arrhythmic Action of Bretylium. Nature 207, 203–204 (1965). https://doi.org/10.1038/207203a0

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