Abstract
IT has been known for some time that alteration of renal function may lead to hypertension. If both kidneys are removed, renoprival hypertension ensues1. If one renal artery is partially constricted and the opposite kidney removed, blood pressure will increase to hypertensive levels2, although renal function is sufficient to maintain essentially normal fluid and electrolyte balance. The latter method is in widespread use as the means of producing hypertension. This communication deals with another method by which hypertension of renal origin may be produced, that is, renal arterial injection of microspheres.
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References
Grollman, A., Muirhead, E. E., and Vanatta, J., Amer. J. Physiol, 157, 21 (1949).
Goldblatt, H., Lynch, J., Hanzal, R. F., and Summerville, W. W., J. Exp. Med., 59, 347 (1934).
Malvin, R. L., J. Lab. Clin. Med., 63, 551 (1964).
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MALVIN, R. Hypertension resulting from Renal Arterial Injection of Microspheres. Nature 206, 938–939 (1965). https://doi.org/10.1038/206938b0
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DOI: https://doi.org/10.1038/206938b0
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