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An Antifungal Triene from a Streptomyces sp.

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Abstract

WHILE polyene antifungal antibiotics are of frequent occurrence among Streptomyces spp., those so far described contain 4–7 double bonds in conjugation. We wish to report the production of an antifungal conjugated triene, MM8, by a Streptomyces sp., ACC 1293. The investigation is incomplete; but as no further work is contemplated we felt that a brief account of our findings might be of interest.

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References

  1. Waksman, S. A., Adv. App. Microbiol., 5, 235 (1963).

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Author notes

  1. J. J. ARMSTRONG & W. B. TURNER

    Present address: Pharmaceuticals Division, Imperial Chemical Industries, Ltd., Alderley Park, Macclesfield, Cheshire

Authors and Affiliations

  1. Imperial Chemical Industries, Ltd., Akers Research Laboratories, The Frythe, Welwyn, Herts.

    J. J. ARMSTRONG, J. F. GROVE, W. B. TURNER & G. WARD

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  1. J. J. ARMSTRONG
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  2. J. F. GROVE
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  3. W. B. TURNER
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  4. G. WARD
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ARMSTRONG, J., GROVE, J., TURNER, W. et al. An Antifungal Triene from a Streptomyces sp.. Nature 206, 399–400 (1965). https://doi.org/10.1038/206399b0

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