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N4-substituted N1-(3-Dimethylaminopropyl)-piperazines : a New Series of Compounds active against Trypanosoma cruzi Infections in Mice

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Abstract

RECENT reviews1–3 on the treatment of Trypanosoma cruzi infections (Chagas's disease, South American trypanosomiasis) in man emphasize the lack of a satisfactory mode of therapy.

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References

  1. World Health Org. Tech. Rep. Ser. No. 202 (Geneva, 1960).

  2. Kollert, W., Clinical Excerpts, 26, 89 (June, 1960) (Bayer, Leverkusen, Germany).

    Google Scholar 

  3. Hawking, F., in Experimental Chemotherapy, edit. by Schnitzer, R. J., and Hawking, F., 1, 129 (Academic Press, New York, 1963).

    Book  Google Scholar 

  4. Hewitt, R., Entwistle, J., and Gill, E., J. Parasit., 49, 22 (1963).

    Article  CAS  Google Scholar 

  5. Pizzi, T., Proc. Soc. Exp. Biol. and Med., 78, 643 (1951).

    Article  CAS  Google Scholar 

  6. Moraes, G. E. S., Faria, J. L., and Fernandes, J. F., Rev. Inst. Med. trop. Sao Paulo, 2, 147 (1960).

    CAS  Google Scholar 

  7. Moon, A. P., and Coleman, J. F., Bol. Chil. Parasit., 17, 63 (1962).

    CAS  Google Scholar 

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Authors and Affiliations

  1. Organic Chemical Research Section and Experimental Therapeutics Research Section, Lederle Laboratories Division, American Cyanamid Co., Pearl River, New York

    ANDREW S. TOMCUFCIK, REDGINAL I. HEWITT, PAUL F. FABIO, ARLENE M. HOFFMAN & JOSEPH ENTWISTLE

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  1. ANDREW S. TOMCUFCIK
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  2. REDGINAL I. HEWITT
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  3. PAUL F. FABIO
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  4. ARLENE M. HOFFMAN
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  5. JOSEPH ENTWISTLE
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TOMCUFCIK, A., HEWITT, R., FABIO, P. et al. N4-substituted N1-(3-Dimethylaminopropyl)-piperazines : a New Series of Compounds active against Trypanosoma cruzi Infections in Mice. Nature 205, 605–606 (1965). https://doi.org/10.1038/205605b0

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