Skip to main content
SpringerLink
Log in

Non-enzymatic Interactions of Reduced Coenzyme I with Inorganic Phosphate and Certain Other Anions

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

WE previously reported1 changes of the absorption spectrum of nicotinamide adenine dinucleotide (coenzyme I, abbreviated NAD+) in solutions containing orthophosphate. In an extension of those investigations2, it has been observed that dihydronicotinamide-adenine dinucleotide (reduced coenzyme I, abbreviated NADH) also reacts with orthophosphate, but in an entirely different manner. Similar changes were observed with dihydronicotinamide adenine dinucleotide phosphate (reduced coenzyme II, abbreviated NADPH) and certain other NADH-analogues. This is a preliminary report of our findings3.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ungar, F., and Alivisatos, S. G. A., Biochim. Biophys. Acta, 46, 406 (1961).

    Article  CAS  PubMed  Google Scholar 

  2. Ungar, F., Abraham, G., and Alivisatos, S. G. A. (in preparation).

  3. Alivisatos, S. G. A., Ungar, F., and Abraham, G. (submitted for publication).

  4. Frost, A. A., and Pearson, R. G., Kinetics and Mechanism, second ed., 166 (John Wiley and Sons, New York, 1961).

    Google Scholar 

  5. Anderson, jun., A. G., and Berkelhammer, G., J. Amer. Chem. Soc., 80, 992 (1958).

    Article  CAS  Google Scholar 

  6. Kosower, E. M., Molecular Biochemistry, 209 (McGraw-Hill, New York, 1962).

    Google Scholar 

  7. Wallenfels, K., Hofmann, D., and Schüly, H., Liebig's Ann. Chem., 621, 188 (1959).

    Article  CAS  Google Scholar 

  8. Weber, G., Nature, 180, 1409 (1957); J. chim. phys., 55, 878 (1958).

    Article  CAS  ADS  Google Scholar 

  9. Chaykin, S., Meinhart, J. O., and Krebs, E. G., J. Biol. Chem., 220, 811 (1956).

    CAS  PubMed  Google Scholar 

  10. Griffiths, D. E., Fed. Proc., 22, 1064 (1963).

    CAS  PubMed  Google Scholar 

  11. Brierley, G., Murer, E., Bachmann, E., and Green, D. E., J. Biol. Chem. 238, 3482 (1963).

    CAS  PubMed  Google Scholar 

  12. Herskovits, T. T., and Laskowski, jun., M., J. Biol. Chem., 237, 2481 (1962).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Enzymology, Chicago Medical School, Chicago

    SPYRIDON G. A. ALIVISATOS, FRIEDA UNGAR & GEORGE ABRAHAM

Authors
  1. SPYRIDON G. A. ALIVISATOS
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. FRIEDA UNGAR
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. GEORGE ABRAHAM
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

ALIVISATOS, S., UNGAR, F. & ABRAHAM, G. Non-enzymatic Interactions of Reduced Coenzyme I with Inorganic Phosphate and Certain Other Anions. Nature 203, 973–975 (1964). https://doi.org/10.1038/203973a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/203973a0

  • Springer Nature Limited

This article is cited by

Search

Navigation