Abstract
THE transfer of immunologically competent cells to an immunologically inert recipient is a technique which has been useful in the examination of the antibody-forming capacity of the donor cells. Under these conditions, circulating antibody may be found in the recipient, if the antigenic stimulation is given to the donor prior to transfer, or to the recipient after transfer1,2. That the donor cells are responsible for the antibody found in the recipient is evident in that disruption of the donor cells eliminates the antibody response.
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COHEN, M., COHEN, E. Proliferation of Transferred Spleen Cells after Antigenic Challenge. Nature 203, 418–419 (1964). https://doi.org/10.1038/203418a0
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DOI: https://doi.org/10.1038/203418a0
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