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Collagen Fibrils of the Scleroderma in Ultra-thin Skin Sections

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Abstract

THE behaviour of dermal collagen fibrils in seleroderma has not often been investigated in ultra-thin skin sections1,2. In our investigations definite pathological alterations of the fine structure of collagen fibrils (axial periodicity, cross-band pattern, internal structure) were not detected either in circumscribed or in progressive scleroderma. As in normal dermis13, an antiparallel arrangement of adjacent fibrils in collagen fibres was found in both types of scleroderma. However, we were led to assume that the quantitative proportion of the two fibril types (R- and L-type) was not approximately 1 : 1 as in normal skin, but changed with a prevaluation of one of the two types.

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References

  1. Bahr, G. F., Ärztl Forsch., 10, 255 (1956).

    Google Scholar 

  2. Fisher, E. R., and Rodnan, G. P., Arthri. and Rheum., 3, 536 (1960).

    Article  CAS  Google Scholar 

  3. Keech, M. K., J. Path. Bact., 77, 351 (1959).

    Article  CAS  Google Scholar 

  4. Korting, G. W., Holzmann, H., and Kühn, K., Arch. klin. exp. Derm., 209, 66 (1959).

    Article  CAS  Google Scholar 

  5. Banfield, W. G., J. Geront., 10, 13 (1955).

    Article  CAS  Google Scholar 

  6. Delaunay, A., and Bazin, S., in Hauss, W. H., and Losse, H., Struktur und Stoffwechsel des Bindegewebes, 70 (G. Thieme, Stuttgart, 1960).

    Google Scholar 

  7. Jackson, S. F., in Tunbridge, R. E., Connective Tissue, 77 (Blackwell, Oxford, and Masson et Cie, Paris, 1957).

    Google Scholar 

  8. Schwarz, W., and Merker, H.-J., Beitr. Sililcose-Forsch., S.Bd. Grundfragen Silikoseforsch, 4, 231 (1960).

    CAS  Google Scholar 

  9. Linke, K. W., Z. Zellforsch., 42, 331 (1955).

    Article  CAS  Google Scholar 

  10. Harkin, J. C., and Kraujitis, A. A., in Breese, jun., S. S., Electron Microscopy, 2 (Academic Press, New York and London, 1962).

    Google Scholar 

  11. Braun-Falco, O., Derm. Wschr., 136, 1085 (1957).

    CAS  PubMed  Google Scholar 

  12. Stoughton, R. B., discussion in Cawley, E. P., McManus, J. F. A., Lupton, Ch. H., and Wheeler, C. E., J. Invest. Derm., 27, 389 (1956).

    Article  Google Scholar 

  13. Braun-Falco, O., and Rupee, M., J. Invest. Derm., 42, 15 (1964).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Dermatological Clinic and Policlinic, Philipps-University, Marburg a. d. Lahn, Germany

    O. BRAUN-FALCO & M. RUPEC

Authors
  1. O. BRAUN-FALCO
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  2. M. RUPEC
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BRAUN-FALCO, O., RUPEC, M. Collagen Fibrils of the Scleroderma in Ultra-thin Skin Sections. Nature 202, 708–709 (1964). https://doi.org/10.1038/202708a0

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