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Induction of Hydronephrosis by Prolonged Intraperitoneal Injections of Sub-toxic Dose of Mitomycin C in Mice

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Abstract

THE method of experimental induction of hydronephrosis by chemical agents has not yet been established, and this forms a bottleneck for research on lesions. During the course of work on the side-effects of anticancer agents, we found many cases of hydronephrosis in SM strain mice injected continuously with subtoxic doses of mitomycin C, an anticancer agent.

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References

  1. Sokoloff, B., Nakabayashi, K., Enomoto, K., Miller, T. R., Bicknell, A., Bird, L., Trauner, W., Niswonger, J., and Renninger, G., Growth, 23, 109 (1959).

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Authors and Affiliations

  1. Department of Pathology, Nagoya City University School of Medicine, Nagoya, Japan

    MUTSUSHI MATSUYAMA, KAORU SUZUMORI & TAKAAKI NAKAMURA

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  1. MUTSUSHI MATSUYAMA
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  2. KAORU SUZUMORI
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  3. TAKAAKI NAKAMURA
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MATSUYAMA, M., SUZUMORI, K. & NAKAMURA, T. Induction of Hydronephrosis by Prolonged Intraperitoneal Injections of Sub-toxic Dose of Mitomycin C in Mice. Nature 202, 99–100 (1964). https://doi.org/10.1038/202099a0

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