Abstract
THE Kasapa strain of Plasmodium berghei, which normally kills mice within three weeks of infection, has been modified by serial passage through tissue culture so that 80 per cent of mice infected with it recover and are immune to reinfection with the culture and parent strains.
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References
Corradetti, A., et al., Parasitol. (Rome), 3 (1/2), 77, 81 (1961).
Damian, R. T., J. Parasitol., 48 (2), Sec. 2 : 2 (1962).
Cameron, G. L., and Staveley, J. M., Nature, 179, 147 (1957).
Rowley, D., and Yenkin, C. R., Nature, 193, 151 (1962).
Markowitz, A. S., et al., Nature, 187, 1095 (1960).
Cohen, S., et al., Nature, 192, 733 (1961).
Tobie, J. E., and Coatney, G. R., Exp. Parasitol., 11, 128 (1961).
Kuvin, S. F., et al., Science, 135, 1130 (1962).
Zuckerman, A., Nature, 185, 189 (1960).
Lourie, E. M., and O'Connor, R. J., Ann. Trop. Med. and Parasitol., 31, 319 (1937).
Ashcroft, M. T., Ann. Trop. Med. and Parasitol., 51, 301 (1957).
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WEISS, M., DEGIUSTI, D. Modification of a Malaria Parasite (Plasmodium berghei) following Passage through Tissue Culture. Nature 201, 731–732 (1964). https://doi.org/10.1038/201731a0
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DOI: https://doi.org/10.1038/201731a0
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