Abstract
IT has recently been suggested that 3-(p-chlorophenyl)-1,1-dimethylurea (CMU) changes specifically the reactivity of excited flavin molecules but has no effect on the photoreduction of other dyes such as phthaleine dyes or methylene blue1. It was argued that the formation of a CMU–flavin complex may be responsible for this effect, particularly since CMU and flavin have ‘similar structures’1,2, thus introducing specificity into the CMU–flavin interaction.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Homann, P., and Gaffron, H., Science, 141, 905 (1963).
Sweetser, P. B., Biochim. Biophys. Acta, 66, 78 (1963).
Radda, G. K., and Calvin, M. (in the press).
Harbury, H. A., and Foley, K. A., Proc. U.S. Nat. Acad. Sci., 44, 662 (1958). Harbury, H. A., Lanoue, K. F., Loach, P. A., and Amick, R. M., ibid., 45, 1708 (1959).
Isenberg, I., and Szent-Györgyi, A., Proc. U.S. Nat. Acad. Sci., 44, 857 (1958).
Weber, G., Biochem. J., 47, 114 (1950).
Bamberg, P., and Hemmerich, P., Helv. Chim. Acta, 44, 1001 (1961).
Clark, W. M., Oxidation-Reduction Potentials of Organic Systems, 483 (Williams and Wilkins Co., Baltimore, 1960).
Lowe, H. J., and Clark, W. M., J. Biol. Chem., 221, 983 (1956).
Holmstrom, B., and Oster, G., J. Amer. Chem. Soc., 83, 1867 (1961).
Sakai, K., Nagoya, J. Med. Sci., 18, 245 (1955).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
RADDA, G., CALVIN, M. Inhibition of the Photoreduction of Flavin Mononucleotide. Nature 200, 464–465 (1963). https://doi.org/10.1038/200464b0
Issue Date:
DOI: https://doi.org/10.1038/200464b0
- Springer Nature Limited
This article is cited by
-
Flavins in a Solid Matrix
Nature (1967)
-
Electronic Effects and L-Amino-Acid Oxidase Specificity
Nature (1964)