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Proton Magnetic Relaxation and Protein Hydration

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Abstract

WE have found that ovalbumin dissolved in water decreases the proton spin–lattice relaxation time T1 and proton spin–spin relaxation time T2 and we show that this effect is due to an increase of correlation time of part of the water molecules. The correlation time τ can be defined as the mean time of persistence of the angular position of a water molecule and is simply related1 to the Debye dielectric relaxation time τd, τ=τd/3. According to the theory of nuclear magnetic relaxation by Solomon2, T1 and T2 are functions of τ. In some cases τ can be expressed as a function of the macroscopic viscosity of the liquid1, but in the case of protein solutions such an explanation is not possible as was shown by Hennel et al.3.

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References

  1. Bloembergen, N., Purcell, E. M., and Pound, R. V., Phys. Rev., 73, 679 (1948).

    Article  ADS  CAS  Google Scholar 

  2. Solomon, I., Phys. Rev., 99, 559 (1955).

    Article  ADS  CAS  Google Scholar 

  3. Hennel, J. W., Hrynkiewicz, A. Z., Krynicki, K., Waluga, T., and Zapalski, G., Arch. Sci. (Geneva), 11, 243 (1958).

    CAS  Google Scholar 

  4. Carr, H. Y., and Purcell, E. M., Phys. Rev., 94, 630 (1954).

    Article  ADS  CAS  Google Scholar 

  5. Meiboom, S., and Gill, D., Rev. Sci. Instr., 29, 688 (1958).

    Article  ADS  CAS  Google Scholar 

  6. Buchanan, T. J., Haggis, G. H., Hasted, J. B., and Robinson, B. G., Proc. Roy. Soc., A, 213, 379 (1952).

    Article  ADS  CAS  Google Scholar 

  7. Sheraga, H. A., Protein Structure, 195 (Academic Press, New York, 1961).

  8. Zimmerman, J. R., and Brittin, W. E., J. Phys. Chem., 61, 1328 (1957).

    Article  CAS  Google Scholar 

  9. Landolt-Börnstein, Zahlenwerte und Funktionen, 6 Aufl., 1, Teil 2, 333 (Springer, Berlin, 1955).

    MATH  Google Scholar 

  10. Edsall, J. T., in The Proteins, edit. by Neurath, H., and Bailey, K., 1, 702 (Academic Press, New York, 1953).

    Google Scholar 

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Authors and Affiliations

  1. Institute of Nuclear Physics, Polish Academy of Sciences,

    O. K.-DASZKIEWICZ, J. W. HENNEL & B. LUBAS

  2. Department of Physiological Chemistry, Medical Academy, Cracow, Poland

    T. W. SZCZEPKOWSKI

Authors
  1. O. K.-DASZKIEWICZ
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  2. J. W. HENNEL
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  3. B. LUBAS
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  4. T. W. SZCZEPKOWSKI
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K.-DASZKIEWICZ, O., HENNEL, J., LUBAS, B. et al. Proton Magnetic Relaxation and Protein Hydration. Nature 200, 1006–1007 (1963). https://doi.org/10.1038/2001006a0

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