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Identification of a Somatic Antigen of Staphylococcus aureus Critical for Phagocytosis by Human Blood Leucocytes

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Abstract

THE capacity of Staphylococcus aureus to produce disease resides in its ability to invade and persist in the body, and in its elaboration of toxic metabolites. Host-defensive mechanisms comprise the elaboration of antibodies which facilitate phagocytosis and intracellular destruction, and the elaboration of antitoxins. This communication reports identification of at least one antigen of the staphylococcal cell-wall which is critical for phagocytosis by human blood leucocytes.

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Authors and Affiliations

  1. United States Veterans Administration Hospital and Department of Public Health and Preventive Medicine, University of Pennsylvania,

    STUART MUDD, AKIRA YOSHIDA, ISABEL W. LI & NANCY A. LENHART

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  1. STUART MUDD
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  2. AKIRA YOSHIDA
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  3. ISABEL W. LI
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  4. NANCY A. LENHART
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MUDD, S., YOSHIDA, A., LI, I. et al. Identification of a Somatic Antigen of Staphylococcus aureus Critical for Phagocytosis by Human Blood Leucocytes. Nature 199, 1200–1201 (1963). https://doi.org/10.1038/1991200a0

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