Abstract
IF a foreign motor nerve is connected to a normally innervated muscle, the nerve fibres grow into it but do not establish intimate contact with muscle fibres, and are unable to transmit impulses to them. On the other hand, if the muscle fibres are deprived of their normal innervation a foreign nerve will establish functional connexions with them1–3.
Similar content being viewed by others
References
Elsberg, C. A., Science, 45, 318 (1917).
Aitken, J. T., J. Anat., 84, 38 (1950).
Guth, L., and Zalewski, A. A., Exp. Neurol., 7, 316 (1963).
Miledi, R., Nature, 193, 281 (1962).
Koenig, J., C.R. Acad. Sci., Paris, 256, 2918 (1963).
Harrison, R. G., J. Exp. Zool., 9, 787 (1910).
Miledi, R., J. Physiol., 154, 190 (1960).
Katz, B., Johns Hopkins Hosp. Bull., 102, 275 (1958).
Katz, B., and Miledi, R., J. Physiol., 156, 24, P (1961).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MILEDI, R. Formation of Extra Nerve-muscle Junctions in Innervated Muscle. Nature 199, 1191–1192 (1963). https://doi.org/10.1038/1991191a0
Issue Date:
DOI: https://doi.org/10.1038/1991191a0
- Springer Nature Limited
This article is cited by
-
Histochemical properties and innervation pattern of fast and slow-tonic fibre types of the anterior latissimus dorsi muscle of the chick
The Histochemical Journal (1982)
-
Competition between foreign and original nerves in adult mammalian skeletal muscle
Nature (1979)
-
Gating properties of acetycholine receptor in newly formed neuromuscular synapses
Nature (1978)
-
Suppression of transmission at foreign synapses in adult newt muscle involves reduction in quantal content
Nature (1976)
-
Ultrastructure of the new neuromuscular junctions formed during reinnervation of rat soleus muscle by a ?foreign? nerve
Cell and Tissue Research (1976)