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Radiochromium-labelled Hæmoglobin Survival in Normal and Pyridoxine-deficient Rats

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Abstract

FAVOURABLE results from treatment of hypochromic anæmias with pyridoxine demonstrated clinically1–4 and in experimental animals5–8 suggest that pyridoxine deficiency might influence hæmoglobin survival times in rats. Comparison of the amounts of intravenously injected chromium-51 associated with hæmoglobin over several weeks indicates that the apparent survival times of the rat hæmoglobin may vary inversely with the extent of labelling with chromium-51.

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Authors and Affiliations

  1. Radioisotope Service, Veterans Administration Hospital, Fort Howard, Maryland

    BERGENE KAWIN

  2. Biochemistry Research Laboratory, Veterans Administration Hospital, Baltimore, Maryland

    JONG M. HSU

Authors
  1. BERGENE KAWIN
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  2. JONG M. HSU
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KAWIN, B., HSU, J. Radiochromium-labelled Hæmoglobin Survival in Normal and Pyridoxine-deficient Rats. Nature 198, 1099–1100 (1963). https://doi.org/10.1038/1981099a0

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