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Axial Period of Fibrinogen and Fibrin

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Abstract

X-RAY diffraction was first applied to the analysis of blood clotting by Bailey, Astbury and Rudall1. The apparent persistence of the α-type wide-angle X-ray diagram when fibrinogen is converted to fibrin led these investigators to conclude that “fibrinogen is no other than an insoluble modification of fibrin without any fundamental change in molecular plan”.

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Authors and Affiliations

  1. Department of Physics, Harvard University, Cambridge, Mass.

    LUBERT STRYER

  2. the Division of Laboratories and Research of the Children's Hospital, The Children's Cancer Research Foundation,

    CAROLYN COHEN & ROBERT LANGRIDGE

  3. the Department of Biophysics, Harvard Medical School, Boston, Mass.

    CAROLYN COHEN & ROBERT LANGRIDGE

Authors
  1. LUBERT STRYER
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  2. CAROLYN COHEN
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  3. ROBERT LANGRIDGE
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STRYER, L., COHEN, C. & LANGRIDGE, R. Axial Period of Fibrinogen and Fibrin. Nature 197, 793–794 (1963). https://doi.org/10.1038/197793a0

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