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A Combined Microphoresis-Autoradiography Technique

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Abstract

BASE ratios can be determined with microelectrophoresis (microphoresis) in as little as 5 × 10−10 g RNA1, a sensitivity which permits intracellular analysis in suitable material. It would be of interest for turn-over studies to evaluate radioactivity in the separated RNA components. Autoradiography is the simplest tool for this purpose, both because of its sensitivity and high resolution.

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References

  1. Edström, J.-E., J. Biophys. Biochem. Cytol., 8, 39 (1960).

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Authors and Affiliations

  1. Institute of Animal Genetics, Edinburgh, 9

    J. L. SIRLIN

  2. Department of Histology and Neurobiology, University of Gothenburg, Sweden

    J.-E. EDSTRÖM

Authors
  1. J. L. SIRLIN
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  2. J.-E. EDSTRÖM
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SIRLIN, J., EDSTRÖM, JE. A Combined Microphoresis-Autoradiography Technique. Nature 197, 89–90 (1963). https://doi.org/10.1038/197089a0

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