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Persistence of Mucopolysaccharide Inclusions in Cultures of Lymphocytes from Patients with Gargoylism

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Abstract

IT has been shown that patients with gargoylism (Hunter–Hurler syndrome) have abnormal deposits of mucopolysaccharides in various organs1. Inclusions of mucopolysaccharide have also been found in a proportion of the lymphocytes from peripheral blood2. We wish to report some observations made on lymphocytes in cell cultures obtained from gargoyle patients.

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References

  1. Brante, G., Cerebral Lipidoses, edit. by Bogaert, L. van (Blackwell, Oxford, 1958).

    Google Scholar 

  2. Mittwoch, U., Nature, 191, 1315 (1961).

    Article  ADS  CAS  Google Scholar 

  3. Hungerford, D. A., Donnelly, A. J., Nowell, P. C., and Beck, S., Amer. J. hum. Genet., 11, 215 (1959).

    CAS  PubMed  Google Scholar 

  4. Mackinney, jun., A. A., Stohlman, jun., F., and Brecher, G., Blood, 19, 349 (1962).

    PubMed  Google Scholar 

  5. Mittwoch, U., Proc. Seventh Cong. Europ. Soc. Hœmat., London, 1959, Part. II, 369 (1960).

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Author notes

  1. JAMES E. BOWMAN and LAWRENCE J. SCHNEIDERMAN: This work was done during the tenure of a Special Research Fellowship from the National Institutes of Health, Division of General Medical Sciences.

  2. URSULA MITTWOCH: External Scientific Staff, Medical Research Council.

Authors and Affiliations

  1. Galton Laboratory, University College, London, W.C.1

    JAMES E. BOWMAN, URSULA MITTWOCH & LAWRENCE J. SCHNEIDERMAN

Authors
  1. JAMES E. BOWMAN
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  2. URSULA MITTWOCH
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  3. LAWRENCE J. SCHNEIDERMAN
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BOWMAN, J., MITTWOCH, U. & SCHNEIDERMAN, L. Persistence of Mucopolysaccharide Inclusions in Cultures of Lymphocytes from Patients with Gargoylism. Nature 195, 612–613 (1962). https://doi.org/10.1038/195612a0

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