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Oxidation of Anthranilic Acid by a Species of Achromobacter isolated from Soil

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Abstract

STUDIES of the microbial decomposition of anthranilic acid have been confined mostly to work with various strains of Pseudomonas spp.1–3 which oxidize anthranilic acid to catechol by an unknown pathway. The role of salicylic acid in this conversion is not clear since reported experiments based on the technique of simultaneous adaptation have yielded divergent results1,4. Sakamoto et al.4 have further shown that cell suspensions, adapted to oxidize anthranilic acid, are inactive towards 3-hydroxyanthranilic acid and 5-hydroxyanthranilic acid. By contrast, the two last-named compounds have been clearly implicated in the breakdown of anthranilic acid by mammalian tissue since both have been isolated from the urine of animals injected with anthranilic acid or o-aminobenzamide5–9.

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Authors and Affiliations

  1. Division of Soils, C.S.I.R.O., Adelaide

    J. N. LADD

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  1. J. N. LADD
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LADD, J. Oxidation of Anthranilic Acid by a Species of Achromobacter isolated from Soil. Nature 194, 1099–1100 (1962). https://doi.org/10.1038/1941099b0

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