Abstract
THE examination of known human genetic differences in cell culture is a prerequisite to the establishment of a somatic cell genetics of man. The recent paper on the inability of cell cultures from galactosæmic subjects to utilize galactose is the first report of the maintenance of a genetically determined metabolic difference in cell culture1. In this communication we wish to report the results of work on glucose-6-phosphate dehydrogenase activities in cell cultures from a subject with a genetically determined deficiency of glucose-6-phosphate dehydrogenase activity and from a series of normal subjects.
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References
Krooth, R. S., and Weinberg, A. N., Biochem. and Biophys. Res. Comm., 3, 518 (1960).
Edwards, J. H., Lancet, i, 496 (1960).
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GARTLER, S., GANDINI, E. & CEPPELLINI, R. Glucose-6-Phosphate Dehydrogenase Deficient Mutant in Human Cell Culture. Nature 193, 602–603 (1962). https://doi.org/10.1038/193602a0
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DOI: https://doi.org/10.1038/193602a0
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