Skip to main content
Log in

Hydrolysis of Glycerides of C-16 and C-18 Fatty Acids by Post-Heparin Plasma

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

SEVERAL investigators have demonstrated that intravenous injection of heparin releases into the plasma of man and several other species a lipase (clearing factor lipase, lipoprotein lipase) which hydrolyses the glyceride moieties of some lipoproteins1. It has also been reported that various triglyceride emulsions, for example, coconut and olive oils, are substrates for the enzyme and that activation of the emulsion with serum high-density lipoproteins increases the rate of hydrolysis of the triglycerides.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Robinson, D. S., and French, J. E., Pharmacol. Rev., 12, 241 (1960).

    CAS  PubMed  Google Scholar 

  2. Korn, E. D., in Methods of Biochemical Analysis, edit. by Glick, D., 7, 145 (Interscience Pub., Inc., New York, 1959).

    Google Scholar 

  3. Shore, B., Nichols, A. V., and Freeman, N. K., Proc. Soc. Exp. Biol. Med., 83, 216 (1953).

    Article  CAS  Google Scholar 

  4. Borgstrom, B., Acta Physiol. Scand., 25, 111 (1952).

    Article  CAS  Google Scholar 

  5. Dole, V. P., J. Clin. Invest., 35, 150 (1956).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

SHORE, B., SHORE, V. Hydrolysis of Glycerides of C-16 and C-18 Fatty Acids by Post-Heparin Plasma. Nature 193, 163–164 (1962). https://doi.org/10.1038/193163a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/193163a0

  • Springer Nature Limited

This article is cited by

Navigation