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Determination of the Amino-Acid Composition of Bovine Growth Hormone

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Abstract

THE amino-acid composition of bovine growth hormone has been determined1 by Levy's method2. This procedure, which involves paper chromatography of dinitrophenyl derivatives of amino-acids, is subject to certain limitations such as variable recoveries of tyrosine and lack of resolution of the leucine derivatives. The development of automated ion-exchange chromatography of amino-acids3 has prompted a re-investigation of the amino-acid composition of this protein.

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References

  1. Li, C. H., and Chung, D., J. Biol. Chem., 218, 33 (1956).

    CAS  PubMed  Google Scholar 

  2. Levy, A. L., Nature, 174, 126 (1954).

    Article  ADS  CAS  Google Scholar 

  3. Spackman, D. H., Stein, W. H., and Moore, S., Anal. Chem., 30, 1190 (1958).

    Article  CAS  Google Scholar 

  4. Li, C. H., J. Biol. Chem., 211, 555 (1954).

    CAS  PubMed  Google Scholar 

  5. Ferguson, K. A., and Wallace, A. L. C., Nature, 190, 629 (1961).

    Article  ADS  CAS  Google Scholar 

  6. Léonis, J., and Li, C. H., Biochim. Biophys. Acta, 28, 520 (1958).

    Article  Google Scholar 

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Authors and Affiliations

  1. Department of Biochemistry, The Upjohn Co., Kalamazoo, Michigan

    ALAN J. PARCELLS

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  1. ALAN J. PARCELLS
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PARCELLS, A. Determination of the Amino-Acid Composition of Bovine Growth Hormone. Nature 192, 971–972 (1961). https://doi.org/10.1038/192971a0

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