Abstract
PREVIOUS investigations1 carried out in one of our laboratories have shown that nucleic acids could be precipitated as quaternary ammonium salts, soluble in various organic solvents, and that they could be regenerated from these organic solutions as the sodium salts on addition of concentrated solutions of sodium chloride. This treatment does not affect the infectivity of tobacco mosaic virus ribonucleic acid (RNA)2.
Similar content being viewed by others
References
Aubel-Sadron, G., Beck, G., Ebel, J. P., and Sadron, C., Biochim. Biophys. Acta, 42, 542 (1960).
Hirth, L., Lebeurrier, G., Aubel-Sadron, G., Beck, G., Ebel, J. P., and Horn, P., Nature, 188, 689 (1960).
Monier, R., Stephenson, M. L., and Zamecnik, P. C., Biochim. Biophys. Acta, 43, 1 (1960).
Hecht, L. P., Zamecnik, P. C., Stephenson, M. L., and Scott, J. F., J. Biol. Chem., 233, 954 (1958).
Bosch, L., Bloemendal, H., and Sluyser, M., Biochim. Biophys. Acta, 41, 444 (1960).
Monier, R., and Legault-Demare, J. (unpublished results).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
WEIL, J., EBEL, J. & MONIER, R. Conservation of the Biological Activity of a Soluble Ribonucleic Acid. Nature 192, 169–170 (1961). https://doi.org/10.1038/192169a0
Issue Date:
DOI: https://doi.org/10.1038/192169a0
- Springer Nature Limited
This article is cited by
-
Molecular biologists, biochemists, and messenger RNA: The birth of a scientific network
Journal of the History of Biology (1996)
-
Helical regions in transfer ribonucleic acid
Biophysik (1966)