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A Relation between the Reactivity of Human Red Cells to Antiglobulin Tests and their Surface Structure

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Abstract

SEVERAL authors1 have suggested that changes in the immunological reactivity of a cell may be correlated with changes in its surface structure. We present evidence here that human red cells giving a positive antiglobulin reaction show changes in their surfaces demonstrable with the electron microscope.

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References

  1. Liu, C. K., and Evans, R. S., Proc. Soc. Exp. Biol. and Med., 79, 194 (1952). Rebuck, J. W., Anat. Rec, 115, 4 (1953). de Vries, A., et al., Harefuah (J. Med. Assoc. Israel) (Jan. 1, 1957). Goldberg, B., and Green, N., J. Exp. Med., 109 (5), 505 (1959).

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Authors and Affiliations

  1. Department of Experimental Pathology and Cancer Research, University of Leeds,

    JUDITH E. DAVIS, H. N. GREEN & PAMELA W. TYMMS

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  1. JUDITH E. DAVIS
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  2. H. N. GREEN
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  3. PAMELA W. TYMMS
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DAVIS, J., GREEN, H. & TYMMS, P. A Relation between the Reactivity of Human Red Cells to Antiglobulin Tests and their Surface Structure. Nature 191, 923–924 (1961). https://doi.org/10.1038/191923a0

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