Abstract
THE possibility of passively transferring delayed hypersensitivity in the guinea pig with viable cells from lymph node, spleen and peritoneal exudate was shown by the work of Landsteiner and Chase1. Since then, a number of workers have tried to identify some subcellular material responsible for the transfer. Jeter, Tremaine and Seebohm2 described the passive transfer of contact sensitivity to 2 : 4-dinitrochloro-benzene with sonically disrupted peritoneal exudate cells, but Eisen3 observed that sonic disruption of lymphoid cells abolished their capacity to transfer contact sensitivity to 2 : 4-dinitrofluorobenzene.
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References
Landsteiner, K., and Chase, M. W., Proc. N.Y. Soc. Exp. Biol. Med., 49, 688 (1942).
Jeter, W. S., Tremaine, M. M., and Seebohm, P. M., Proc. N.Y. Soc. Exp. Biol. Med., 86, 251 (1954).
Eisen, H. N., in Cellular and Humoral Aspects of the Hypersensitive State, 89 (Paul B. Hoeber, Inc., New York, 1959).
Chase, M. W., Int. Arch. Allergy, 3, 163 (1954).
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Rapp, H. J., Sims, M. R., and Borsos, T., Proc. N.Y. Soc. Exp. Biol. Med., 100, 733 (1959).
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TURK, J. Passive Transfer of Contact Sensitivity to Picryl Chloride in Guinea Pigs, with Subcellular Material. Nature 191, 915–916 (1961). https://doi.org/10.1038/191915a0
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DOI: https://doi.org/10.1038/191915a0
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