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Identification of So-called Atypical Macroglobulinæmia as an Atypical Form of β2A-Paraproteinæmia: a New Immunological Entity?

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Abstract

OCCASIONALLY, ultracentrifugation of sera from patients with multiple myeloma yields an abnormal protein fraction with a sedimentation constant of 8–12 S. Jahnke and Scholtan1 referred to such cases as “atypical macroglobulinæmia”, because the sedimentation constant of these pathological proteins is smaller than that of the ‘true’ macroglobulins such as found in Waldenström's macroglobulinæmia.

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References

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Authors and Affiliations

  1. Medical Department, University Hospital, Utrecht

    R. E. BALLIEUX, J. W. IMHOF & G. H. NIEHAUS

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  1. R. E. BALLIEUX
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  2. J. W. IMHOF
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  3. G. H. NIEHAUS
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BALLIEUX, R., IMHOF, J. & NIEHAUS, G. Identification of So-called Atypical Macroglobulinæmia as an Atypical Form of β2A-Paraproteinæmia: a New Immunological Entity?. Nature 189, 768–770 (1961). https://doi.org/10.1038/189768a0

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