Abstract
Crane, Hatefi, Lester and Widmer1,2 have shown that coenzyme Q is reduced by mitochondria or derivative particles like electron-transporting particles, or succinic dehydrogenase complex, and that this reaction is sensitive to antimycin A. We have now succeeded in reducing coenzyme Q with a soluble preparation of succinic acid dehydrogenase, and this reaction was not sensitive to antimycin A.
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References
Crane, F. L., Hatefi, Y., Lester, R. L., and Widmer, C., Biochim. Biophys. Acta, 25, 220 (1957).
Hatefi, Y., Lester, R. L., Crane, F. L., and Widmer, C., Biochim. Biophys. Acta, 31, 490 (1959).
Neufeld, H. A., Scott, C. R., and Stotz, E., J. Biol. Chem., 210, 869 (1954).
Slater, E. C., Biochem. J., 45, 1 (1949).
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HELLER, J., SZARKOWSKA, L. & PETRYSZYN, C. Reduction of Coenzyme Q by Succinic Acid Dehydrogenase. Nature 189, 578–579 (1961). https://doi.org/10.1038/189578a0
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DOI: https://doi.org/10.1038/189578a0
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Reduction of Coenzyme Q by Succinic Acid Dehydrogenase
Nature (1961)