References
du Vigneaud, V., Fitch, A., Pekarek, E., and Lockwood, W. W., J. Biol. Chem., 94, 233 (1931).
Nicol, D. S. H. W., Biochim. Biophys. Acta, 34, 257 (1959).
Fisher, R. B., and Zachariah, P., Biochem. J., 76, 155 (1960).
Langdon, R. G., J. Biol. Chem., 235, pc 15 (1960).
Swan, J. M., Nature, 180, 643 (1957).
Mycek, M. J., Clark, D. D., Neidle, A., and Waelsch, H., Arch. Biochem. Biophys., 84, 528 (1959).
Leggett Bailey, J., and Cole, R. D., J. Biol. Chem., 234, 1733 (1959).
Wardlaw, A. C., and Moloney, P. J., Canad. J. Biochem. Physiol. (in the press).
Young, D. M., and Lewis, A. H., Science, 105, 368 (1947).
Moloney, P. J., and Coval, M., Biochem. J., 59, 179 (1955).
White, F. H., Fed. Proc., 19, 333 (1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DIXON, G., WARDLAW, A. Regeneration of Insulin Activity from the Separated and Inactive A and B Chains. Nature 188, 721–724 (1960). https://doi.org/10.1038/188721a0
Issue Date:
DOI: https://doi.org/10.1038/188721a0
- Springer Nature Limited
This article is cited by
-
Selenium chemistry for spatio-selective peptide and protein functionalization
Nature Reviews Chemistry (2024)
-
Characterization and optimization of two-chain folding pathways of insulin via native chain assembly
Communications Chemistry (2018)
-
In vitro insulin refolding: Characterization of the intermediates and the putative folding pathway
Science in China Series C: Life Sciences (2007)
-
A study of human recombinant insulin S-sulfonation conditions
Pharmaceutical Chemistry Journal (1993)
-
Reoxidation of reduced hen egg white lysozyme fragment 1–123
Experientia (1978)