Abstract
MANNING et al. 1 have discussed the applicability of the glucostatic theory of Mayer et al. 2 to the regulation of food intake in sheep. Glucose in ruminant animals plays a relatively minor part in energy metabolism, since a major portion of ingested carbohydrates are degraded to volatile fatty acids which are absorbed into the blood stream via the rumen wall3. Consequently, a chemoreceptor mechanism of regulation of intake in ruminants may depend on any of several metabolites. The objective of this experiment was to examine several major intermediate metabolites for their effect on appetite.
Similar content being viewed by others
References
Manning, R., Alexander, G. I., Krueger, H. M., and Bogart, R., Amer. J. Vet. Res., 20, 242 (1959).
Mayer, J., and Bates, M. W., Amer. J. Physiol., 168, 812 (1952).
Barcroft, J., McAnally, R. A., and Phillipson, A. T., J. Exp. Biol., 20, 120 (1944).
National Research Council Publication 464 (1956) gives daily maintenance requirement of a 1,000-lb. cow as 14.1 therms of digestible energy; adjustments for variation in body-weight were proportional to 0.75 log body-weight.
Vallance, W. S., and McClymont, G. L., Nature, 183, 446 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DOWDEN, D., JACOBSON, D. Inhibition of Appetite in Dairy Cattle by Certain Intermediate Metabolites. Nature 188, 148–149 (1960). https://doi.org/10.1038/188148a0
Issue Date:
DOI: https://doi.org/10.1038/188148a0
- Springer Nature Limited
This article is cited by
-
Comportement alimentaire du mouton effets de la nialamide et de la 6-hydroxydopamine
Psychopharmacologia (1974)
-
Mechanismen zur Regulierung der Nahrungsaufnahme und deren Beeinflussung durch endogene und exogene Faktoren
Klinische Wochenschrift (1969)
-
Stoffwechseluntersuchungen mit Essig-, Milch- und Citronens�ureII. Mitteilung Verteilung von zugef�hrter Essig- und Citronens�ure im Tierk�rper
Zeitschrift f�r Lebensmittel-Untersuchung und -Forschung (1966)
-
Chemostatic Regulation of Appetite in Sheep
Nature (1963)