Skip to main content

Advertisement

SpringerLink
Log in

Protection against Liver Injury due to Murine Hepatitis Virus

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

PREVIOUS work has shown that antihistamine drugs protect against liver injury caused by a variety of agents1 both in the whole animal and in vitro. Judah has also shown that these compounds inhibit mitochondrial swelling in vitro, and has indicated a possible mechanism of action2,3. McLean4 has shown that the antihistamine ‘Phenergan’ will protect rats against nutritional liver necrosis and has demonstrated in vitro effects of this drug with slices cut from the livers of rats on necrogenic diets.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Gallagher, C. H., Gupta, D. N., Judah, J. D., and Rees, K. R., J. Path. Bact., 72, 193 (1956).

    Article  CAS  PubMed  Google Scholar 

  2. Judah, J. D., Nature, 185, 390 (1960); Exp. Cell Res., 19, 404 (1960).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Judah, J. D., Nature (preceding communication).

  4. McLean, A. E. M., Nature, 185, 191 and 936 (1960).

    Article  ADS  CAS  Google Scholar 

  5. Dick, C. W. A., Niven, J. S., and Gledhill, A. W., Brit. J. Exp. Path., 37, 90 (1956).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Bang, F. B., and Warwick, A., Virology, 9, 716 (1959).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Wistar Institute of Anatomy and Biology, Philadelphia, Pa.

    J. D. JUDAH, G. BJOTVEDT & T. VAINIO

Authors
  1. J. D. JUDAH
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. BJOTVEDT
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. T. VAINIO
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

JUDAH, J., BJOTVEDT, G. & VAINIO, T. Protection against Liver Injury due to Murine Hepatitis Virus. Nature 187, 507–508 (1960). https://doi.org/10.1038/187507a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/187507a0

  • Springer Nature Limited

This article is cited by

Search

Navigation