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Biogenesis of Ascorbigen, 3-Indolylacetonitrile and Indole-3-carboxylic Acid from D,L-Tryptophan-3-14C in Brassica oleracea L.

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Abstract

DURING earlier work we found that ascorbigen (the bound form of ascorbic acid) is an indole derivative1–5. In view of the fact that the indole moiety of ascorbigen possesses a carbon skeleton identical with that of tryptophan, the hypothesis was put forward that this amino-acid3, as well as 3-indolylpyruvic acid6, may be the precursor of the synthesis in vivo of ascorbigen. In preliminary experiments we found that the level of ascorbigen in kohlrabi was raised after the injection of tryptophan into the bulb7.

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KUTÁČEK, M., PROCHÁZKA, Ž. & GRÜNBERGER, D. Biogenesis of Ascorbigen, 3-Indolylacetonitrile and Indole-3-carboxylic Acid from D,L-Tryptophan-3-14C in Brassica oleracea L.. Nature 187, 61–62 (1960). https://doi.org/10.1038/187061a0

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