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Infra-Red Spectra of Deoxyribonucleic Acids from Human Leucocytes

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Abstract

AS part of a study on the physico-chemical behaviour of deoxyribonucleic acid obtained from human leukæmic leucocytes, we have examined the infra-red spectra of many normal and leukæmic samples in solutions in water and deuterium and in the dry state. Since we did not find complete agreement between previous reports of the infra-red spectra of calf thymus deoxyribonucleic acid1–3, we have also studied samples from this source. The effects of heating, pH changes, degradation with deoxyribonuclease, mild and strong acid hydrolysis were examined and the spectrum of apurinic acid has also been determined.

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References

  1. Blout, E. R., and Lenormant, H., Biochim. Biophys. Acta, 17, 325 (1955).

    Article  CAS  Google Scholar 

  2. DeLozé, Chr., Ann. de Chim., 13, 161 (1958).

    Google Scholar 

  3. Sutherland, G. B. B. M., and Tsuboi, M., Proc. Roy. Soc., A, 239, 446 (1957).

    Article  ADS  CAS  Google Scholar 

  4. Blout, E., and Lenormant, H., J. Opt. Soc. Amer., 43, 1093 (1953).

    Article  ADS  CAS  Google Scholar 

  5. Villa, L., Polli, E., Semenza, G., Sensi, A., and di Majorca, G. P., Rev. Belg. de Path., xxxiv, 5, 360 (1955).

    Google Scholar 

  6. Miles, H. T., Biochim. Biophys. Acta, 30, 326 (1958).

    Article  Google Scholar 

  7. Miles, H. T., Nature, 183, 1814 (1959).

    Article  ADS  CAS  Google Scholar 

  8. Miles, H. T., Biochim. Biophys. Acta, 35, 274 (1959).

    Article  CAS  Google Scholar 

  9. Rich, A. A., Rev. Mod. Phys., 31, 191 (1959).

    Article  ADS  CAS  Google Scholar 

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Author notes

  1. G. ZERBI

    Present address: University of Minnesota School of Chemistry, Minneapolis, Minnesota

Authors and Affiliations

  1. Istituto di Chimica Industriale del Politecnico, Milano

    G. ZERBI

  2. Istituto di Clinica Medica Generale, Università di Milano,

    P. A. BIANCHI & E. E. POLLI

Authors
  1. G. ZERBI
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  2. P. A. BIANCHI
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  3. E. E. POLLI
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ZERBI, G., BIANCHI, P. & POLLI, E. Infra-Red Spectra of Deoxyribonucleic Acids from Human Leucocytes. Nature 186, 964–965 (1960). https://doi.org/10.1038/186964a0

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