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Anticholinergic Activity of Tropine-α-Methyltropate

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Abstract

THE synthesis of the new α-methyltropic ester of tropine and the isolation of the two optically active isomers has been recently described by Melone, Vecchi, Pagani and Testa1.

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References

  1. Melone, G., Vecchi, A., Pagani, G., and Testa, E., J. Org. Chem. (in the press).

  2. Foster, R., and Ing, H. R., J. Chem. Soc., 938 (1956).

  3. Bovet, D., and Bovet-Nitti, F., “Structure et Activité des Médicaments du Système Nerveux végétatif”, 500 (S. Karger, Basle, 1948).

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  4. Goodman, L. S., and Gilman, A., “The Pharmacological Basis of Therapeutics”, second edit., 551 (The Macmillan Co., New York, 1956).

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  5. Litchfield, J. T., and Wilcoxon, F., J. Pharm. Exp. Therap., 96, 99 (1949).

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Authors and Affiliations

  1. Pharmacological Department, Research Laboratories, Lepetit S.p.A., Milan

    G. MAFFII & G. BIANCHI

Authors
  1. G. MAFFII
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  2. G. BIANCHI
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MAFFII, G., BIANCHI, G. Anticholinergic Activity of Tropine-α-Methyltropate. Nature 185, 844–845 (1960). https://doi.org/10.1038/185844a0

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