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Pyridoxal Phosphate: a Coenzyme for Histidine Decarboxylase

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Abstract

ALTHOUGH the role of pyridoxal phosphate as a coenzyme of amino-acid decarboxylases is generally recognized, attempts to demonstrate its participation in the enzymic decarboxylation of histidine have hitherto been unsuccessful.1

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References

  1. Gale, E. F., Brit. Med. Bull., 9, 135 (1953).

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  2. Furth, J., Hagen, P., and Hirsch, E., Proc. Soc. Exp. Biol. Med., 95, 824 (1957).

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Authors and Affiliations

  1. Departments of Pharmacology and Pathology and Children's Hospital Cancer Research Foundation, Harvard Medical School, Boston, Mass.

    S. ONO & P. HAGEN

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  1. S. ONO
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  2. P. HAGEN
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ONO, S., HAGEN, P. Pyridoxal Phosphate: a Coenzyme for Histidine Decarboxylase. Nature 184, 1143–1144 (1959). https://doi.org/10.1038/1841143a0

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