Abstract
FOLLOWING the injection of nicotinamide, large increases in the diphosphopyridine nucleotide content of mouse tissues, particularly liver, have been reported by Kaplan and co-workers1. Although it is thought that diphosphopyridine nucleotide is synthesized from adenine mononucleotide, the increase in the former is accompanied by an increase in the total acid-soluble adenine content of the liver.
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References
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THRELFALL, C. Synthesis of Diphosphopyridine Nucleotide from Nicotinamide by Slices of Liver. Nature 184, 60–61 (1959). https://doi.org/10.1038/184060b0
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DOI: https://doi.org/10.1038/184060b0
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