Abstract
RECURRENT inhibition via interneurones (Renshaw cells) was recently invoked by Brooks and Wilson1 to account for changes in monosynaptic spinal reflexes following antidromic activation. This mechanism, which confines stretch reflexes to their paths of afferent origin, operates through a cholinergic synapse between the motoneurone axon collateral and the Renshaw cell2, which liberates an unknown inhibitory transmitter. Presumably the same mechanism functions with respect to disynaptic pathways through the cord. The purpose of this communication is to describe an analogous system in the cerebral cortex of dogs, operated under ether and immobilized by succinylcholine.
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References
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MORRELL, R. Recurrent Inhibition in Cerebral Cortex. Nature 183, 979–980 (1959). https://doi.org/10.1038/183979a0
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DOI: https://doi.org/10.1038/183979a0
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