Skip to main content
SpringerLink
Log in

Effect of Tranquillizing Agents on the Resistance of Rats to Histamine Stress

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

IN view of the long-continued interest in the relationship of histamine to metabolic processes and disorders, most particularly allergy and psychosis, the present investigation sought to explore the effects of prolonged administration of various tranquillizers on response in the rat to histamine, including effects on such variables as histamine LD50, mortality and alterations in body-weight.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Finney, D. J., “Probit Analysis”, 2nd ed. (Cambridge Univ. Press, Cambridge, 1952).

    MATH  Google Scholar 

  2. Gaunt, R., Renzi, A. A., Antonchak, N., Miller, G. J., and Gilman, M., Ann. New York Acad. Sci., 59, 22 (1954).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratories for Therapeutic Research, Research Institute of the Brooklyn College of Pharmacy, Long Island University, Brooklyn, New York

    ARTHUR M. SACKLER, A. S. WELTMAN & RAYMOND R. SACKLER

  2. The van Ophuijsen Center, New York

    ARTHUR M. SACKLER, A. S. WELTMAN & RAYMOND R. SACKLER

Authors
  1. ARTHUR M. SACKLER
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. S. WELTMAN
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. RAYMOND R. SACKLER
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SACKLER, A., WELTMAN, A. & SACKLER, R. Effect of Tranquillizing Agents on the Resistance of Rats to Histamine Stress. Nature 183, 896–897 (1959). https://doi.org/10.1038/183896a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/183896a0

  • Springer Nature Limited

Search

Navigation