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Increase of Viral Hæmagglutinability of Red Cells of the Mouse after Treatment with Formalin

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Abstract

Clark and Nagler1 found that the red cells of the mouse did not react very well with viral hæmagglutinin. Flick2,3, and later on Cox and Pirtle4, introduced the use of human red cells treated with formalin in the study of hæmagglutination by influenza virus. We found, while using formalin to stabilize the red cells of fowl and mouse for viral hæmagglutination, that the hæmagglutinability of those of the latter was considerably enhanced, particularly for certain types of influenza virus.

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References

  1. Clark, E., and Nagler, F. P. O., Aust. J. Biol. Med. Sci., 21, 103 (1943).

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  2. Flick, J. A., Proc. Soc. Exp. Biol. Med., 68, 448 (1948).

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Authors and Affiliations

  1. Centre National de la Grippe, Institut Pasteur, 28 rue du Docteur Roux, Paris, 15

    B. FAUCONNIER & D. BARUA

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  1. B. FAUCONNIER
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  2. D. BARUA
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FAUCONNIER, B., BARUA, D. Increase of Viral Hæmagglutinability of Red Cells of the Mouse after Treatment with Formalin. Nature 183, 629–630 (1959). https://doi.org/10.1038/183629b0

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