Skip to main content

Advertisement

SpringerLink
Log in

A Cytopathogenic Agent from a Mammary Tumour in a C3H Mouse that produces Tumours in Swiss Mice and Hamsters

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

Stewart, Eddy et al. 1–3 recently reported that an agent derived from leukæmic AK mouse tissue produces a cytopathogenic effect in cultures of mouse embryo cells. Furthermore, after passage in tissue culture, this agent, which they term the S.E. Polyoma virus, produces a variety of tumours when it is injected into newborn Swiss mice and hamsters. This report describes observations on an agent with similar properties but derived from a different source.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Eddy, B. E., Stewart, S. E., and Berkeley, W., Proc. Soc. Exp. Biol. Med., 98, 848 (1958).

    Article  CAS  Google Scholar 

  2. Stewart, S. E., Eddy, B. E., Gochenour, A. M., Borghese, N. G., and Grubbs, G. E., Virology, 3, 380 (1957).

    Article  CAS  Google Scholar 

  3. Eddy, B. E., Stewart, S. E., Young, R., and Mider, G. B., J. Nat. Cancer Inst., 20, 747 (1958).

    CAS  Google Scholar 

  4. Parker, R. C., Castor, L. N., and McCulloch, E. A., Special Publication N.Y. Acad. Sci., 5, 303 (1957).

    Google Scholar 

  5. Gross, L., Proc. Soc. Exp. Biol. Med., 88, 362 (1955).

    Article  CAS  Google Scholar 

  6. Mirand, E. A., Mount, D. T., Moore, G. E., Grace, jun., L. T., and Sokal, J. E., Proc. Soc. Exp. Biol. Med., 99, 1 (1958).

    Article  CAS  Google Scholar 

  7. Buffett, R. F., Commerford, S. L., Furth, J., and Hunter, M. J., Proc. Soc. Exp. Biol. Med., 99, 401 (1958).

    Article  CAS  Google Scholar 

  8. Bittner, J. J., Science, 84, 162 (1936).

    Article  ADS  CAS  Google Scholar 

  9. Bittner, J. J., Harvey Lectures Ser., 42, 221 (1946–47).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Medicine and Medical Biophsics, University of Toronto,

    E. A. McCULLOCH, A. F. HOWATSON, L. SIMINOVITCH, A. A. AXELRAD & A. W. HAM

  2. Division of Biological Research, Ontario Cancer Institute, Toronto

    E. A. McCULLOCH, A. F. HOWATSON, L. SIMINOVITCH, A. A. AXELRAD & A. W. HAM

Authors
  1. E. A. McCULLOCH
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. F. HOWATSON
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. L. SIMINOVITCH
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. A. AXELRAD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. W. HAM
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

McCULLOCH, E., HOWATSON, A., SIMINOVITCH, L. et al. A Cytopathogenic Agent from a Mammary Tumour in a C3H Mouse that produces Tumours in Swiss Mice and Hamsters. Nature 183, 1535–1536 (1959). https://doi.org/10.1038/1831535a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1831535a0

  • Springer Nature Limited

This article is cited by

Search

Navigation