Abstract
INVESTIGATIONS of lipid deposits connected with atherosclerosis have usually been concerned with the lipids from the plaques formed in the intima of the aorta1. Although the condition of the aorta is a guide to the progress of the disease, dysfunction due to atherosclerosis is most liable to occur in the smaller arteries, especially coronary and cerebral arteries. It has generally been assumed that lipid deposition in these arteries occurs in a similar way to that in the aorta. If this is so, the composition of the lipids deposited should be approximately the same. Lipids extracted from different atheromatous arteries have been examined in order to test this assumption.
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References
See, for example, Luddy, F. E., Barford, R. A., Riemenschneider, R. W., and Evans, J. D., J. Biol. Chem., 232, 843 (1958). Tuna, N., Reckers, L., and Frantz, I. D., J. Clin. Invest., 37, 1153 (1958).
Cf. Lea, C. H., and Rhodes, D. N., Biochem. J., 54, 467 (1953).
Van Beers, G. J., de Iongh, H., and Boldingh, J., Internat. Conf. on Biochem. Problems of Lipids, Fourth Conf., Essential Fatty Acids, Oxford (1957).
Borgström, B., Acta Physiol. Scand., 25, 111 (1952).
World Health Org., Tech. Rep. Ser., 143, 4 (1958).
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BÖTTCHER, C., WOODFORD, F., TER HAAR ROMENY, C. et al. Composition of Lipids isolated from the Aorta, Coronary Arteries and Circulus Willisii of Atherosclerotic Individuals. Nature 183, 47–48 (1959). https://doi.org/10.1038/183047b0
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DOI: https://doi.org/10.1038/183047b0
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