Skip to main content
SpringerLink
Log in

The High-Energy Proton Beam as a Neurosurgical Tool

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

IRRADIATION with high-energy heavy particles is suitable for the destruction of small selected regions in the central nervous system. Tobias et al.1 irradiated the hypophysis of animals and man with 190-MeV. deuterons and 340-MeV. protons. Anderson et al.2 made lesions in the hypothalamus of the rat using 190-MeV. deuterons. Malis et al.3, making use of the thin ionization peak at the end of the beam, produced lesions at a depth of 0.8 mm. in the cerebral cortex of the cat with 10-MeV. protons. The continuation of animal experiments and the possible application of heavy-particle beams to stereotaxic radiosurgery in man4 5 make it essential to know their effects on the central nervous system in detail.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Tobias, C. A., Roberts, J. E., Lawrence, J. H., Low-Beer, B. V. A., Anger, H. O., Born, J. L., McCombs, R., and Huggins, C., “Peaceful Uses of Atomic Energy”, Proc. Internat. Conf. Geneva, 10, 95 (1955).

    Google Scholar 

  2. Andersson, A., Garcia, J., Henry, J., Riggs, C., Roberts, J. E., Thorell, B., and Tobias, C. A., Radiation Res., 7, 299 (1957).

    Google Scholar 

  3. Malis, L. I., Loevinger, R., Kruger, L., and Rose, J. E., Science, 126, 302 (1957).

    Article  ADS  CAS  Google Scholar 

  4. Leksell, L., Acta Chir. Scand., 102, 316 (1951).

    CAS  PubMed  Google Scholar 

  5. Leksell, L., Herner, T., and Lidén, K., Kgl. fysiogr. Sällsk. Lund Förh., 25, 142 (1955).

    Google Scholar 

  6. Larsson, B., Leksell, L., Rexed, B., and Sourander, P., Acta Radiol. (in the press).

  7. Leksell, L., “Handb. d. Neurochirurgie”, 6 (Springer, Berlin, 1957).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Gustaf Werner Institute for Nuclear Chemistry, and Institute of Anatomy, University of Uppsala,

    BÖRJE LARSSON, LARS LEKSELL, BROR REXED, PATRICK SOURANDER, WILLIAM MAIR & BENGT ANDERSSON

Authors
  1. BÖRJE LARSSON
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. LARS LEKSELL
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. BROR REXED
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. PATRICK SOURANDER
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. WILLIAM MAIR
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. BENGT ANDERSSON
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

LARSSON, B., LEKSELL, L., REXED, B. et al. The High-Energy Proton Beam as a Neurosurgical Tool. Nature 182, 1222–1223 (1958). https://doi.org/10.1038/1821222a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/1821222a0

  • Springer Nature Limited

This article is cited by

Search

Navigation