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Radioprotective Properties of Cystamine, Cysteamine and Cysteine when tested with Chick Fibroblasts in vitro

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Abstract

IT is well known that a number of SH-containing compounds afford a certain amount of radioprotection to many organisms1,2. However, little information is available about the effects on cells in vitro. The present report deals with a series of experiments on the effects of cystamine, cysteamine and cysteine when added to cultures of chick fibroblasts shortly before irradiation.

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References

  1. Patt, H. M., Physiol. Rev., 33, 35 (1953).

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  2. Bacq, Z. M., and Alexander, P., “Fundamentals of Radiobiology” (Butterworth, London, 1955).

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  3. Gray, L. H., “Progress in Radiobiology”, Proc. 4th Int. Conf. on Radiobiol., Cambridge, 1955, 267 (Oliver and Boyd, London 1956).

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  4. Eldjarn, L., Pihl, A., and Shapiro, B., Proc. Int. Conf. on the Peaceful Uses of Atomic Energy, 11, 335 (United Nations, New York, 1956).

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Authors and Affiliations

  1. Norsk Hydros Institute for Cancer Research, The Norwegian Radium Hospital, Oslo

    P. OFTEDAL, R. OFTEBRO & R. EKER

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  1. P. OFTEDAL
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  2. R. OFTEBRO
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  3. R. EKER
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OFTEDAL, P., OFTEBRO, R. & EKER, R. Radioprotective Properties of Cystamine, Cysteamine and Cysteine when tested with Chick Fibroblasts in vitro . Nature 181, 344–345 (1958). https://doi.org/10.1038/181344b0

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