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Enzymatic Cleavage and Synthesis of L-threo-β-Phenylserine and L-erythro-β-Phenylserine

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Abstract

As has been demonstrated in earlier communications, D,L-threo-β-phenylserine-3-14C and D,L-phenylalanine-3-14C are incorporated into the benzoyl moiety of urinary hippuric acid1,2. These results led to the assumption of an enzymatic, in vivo splitting between C2 and C3 of the side-chain, as has been found to occur in vitro for L-phenylserines3,4.

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References

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BRUNS, F., FIEDLER, L. Enzymatic Cleavage and Synthesis of L-threo-β-Phenylserine and L-erythro-β-Phenylserine. Nature 181, 1533–1534 (1958). https://doi.org/10.1038/1811533a0

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