Abstract
DEFORMATION of mechano-receptors gives rise to generator potentials which in turn eventually set up propagated potentials. In order to analyse generator potentials it is desirable to block the propagated potential. In the Pacinian corpuscle this may be done by the aid of drugs, by changing the ionic environment of the receptor1 or, as here reported, by taking advantage of differences in duration of the refractory period of generator and propagated events. Generator potentials alone are obtained when the deformation of the receptor occurs during the refractory period of the propagated potential.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Gray, J. A. B., and Sato, M., J. Physiol., 129, 594 (1955).
Loewenstein, W. R., and Altamirano-Orrego, R., Nature, 178, 1292 (1956).
Gray, J. A. B., and Malcolm, J. L., Proc. Roy. Soc., B, 137, 96 (1950).
Diamond, J., Gray, J. A. B., and Sato, M., J. Physiol., 133, 54 (1956).
Alvarez-Buylla, R., and Ramlrez de Arellano, J. R., Amer. J. Physiol., 172, 237 (1953).
Grundfest, H., Ann. N.Y. Acad. Sci. (in the press).
Loewenstein, W. R., J. Physiol., 133, 588 (1956).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LOEWENSTEIN, W., ALTAMIRANO-ORREGO, R. Generation and Propagation of Impulses during Refractoriness in a Pacinian Corpuscle. Nature 181, 124–125 (1958). https://doi.org/10.1038/181124b0
Issue Date:
DOI: https://doi.org/10.1038/181124b0
- Springer Nature Limited
This article is cited by
-
�ber die Wirkungskette zwischen Reiz und Erregung
Zeitschrift f�r Vergleichende Physiologie (1963)