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Microchemical Method for the Determination of Sakaguchi-positive Antibiotics

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Abstract

ANTIBIOTICS of actinomycete origin containing a guanidine group (such as streptomycin and viomycin) are known to have an antitubercular action. Recently a new antibiotic, primycin, was described1 as an agent active against various mycobacteria and Gram-positive pathogens (0.02 µgm./ml.), and also giving a positive Sakaguchi reaction.

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References

  1. Vályi-Nagy, T., Uri, J., and Szilágyi, I., Nature, 174, 1105 (1954).

    Article  ADS  Google Scholar 

  2. Sakaguchi, S., Biochem. J., 5, 25 (1925); Jap. Med. J., 1, 278 (1948).

    CAS  Google Scholar 

  3. Weber, C. J., J. Biol. Chem., 86, 217 (1930).

    CAS  Google Scholar 

  4. Kraut, H., Schrader-Beistein, E., and Weber, M., Hoppe-Seyl. Z. phys. Chem., 286, 248 (1951).

    Article  CAS  Google Scholar 

  5. Ziegler, K., Späth, A., Schaaf, E., Schumann, W., and Winkelmann, E., Liebigs Ann. Chem., 551, 80 (1942).

    Article  CAS  Google Scholar 

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SZILÁGYI, I., SZABÓ, I. Microchemical Method for the Determination of Sakaguchi-positive Antibiotics. Nature 181, 52–53 (1958). https://doi.org/10.1038/181052a0

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