References
Ingram, V. M., Nature, 178, 792 (1956).
Michl, H., Monatsh. Chem., 82, 489 (1951).
Sanger, F., and Tuppy, H., Biochem. J., 49, 463, 481 (1951). Sanger, F., and Thompson, E. O. P., Biochem. J., 53, 353, 356 (1953).
Fraenkel-Conrat, H., Harris, J. I., and Levy, A. L., “Methods of Biochemical Analysis” 2, 359 (1955).
Edman, P., Acta Chem. Scand., 4, 277, 283 (1950).
Perutz, M. F., Liquori, A. M., and Eirich, F., Nature, 167, 929 (1951).
Schroeder, W. A., Rhinesmith, H. S., and Pauling, L. (in the press).
Havinga E., and Itano, H. A., Proc. U.S. Nat. Acad. Sci., 39, 65 (1953).
Pauling, L., Itano, H. A., Singer, S. J., and Wells, I. C., Science, 110, 543 (1949).
Scheinberg, I. H., Harris, R. S., and Spitzer, J. L., Proc. U.S. Nat. Acad. Sci., 40, 777 (1954).
Harris, J. I., Sanger, F., and Naughton, M. A., Arch. Biochem. Biophys., 65, 427 (1956).
Neel, J. V., Science, 110, 64 (1949).
Haldane, J. B. S., “Biochemistry of Genetics” (Allen and Unwin, London, 1954).
Benzer, S., in “The Chemical Basis of Heredity”, edit. by McElroy, W. D., and Glass, B., 70 (Johns Hopkins Press, Baltimore, 1957).
Streisinger, G., and Franklin, N. C., Cold Spring Harbor Symp. Quant. Biol., 21, 103 (1956).
Pritchard, R. H., Heredity, 9, 343 (1955).
Giles, N. H., Partridge, C. W. H., and Nelson, N. J., Proc. U.S. Nat. Acad. Sci., 43, 305 (1957).
Itano, H. A., Ann. Rev. Biochem., 25, 331 (1956).
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INGRAM, V. Gene Mutations in Human Hæmoglobin: the Chemical Difference Between Normal and Sickle Cell Hæmoglobin. Nature 180, 326–328 (1957). https://doi.org/10.1038/180326a0
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DOI: https://doi.org/10.1038/180326a0
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