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Rise of Serum Folic Acid - Levels after Injection of Vitamin B12 in Nutritional Macrocytic Anæmia

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Abstract

ALTHOUGH certain similarities between folic acid and vitamin B12 as agents involved in hæmopoiesis, nucleic acid synthesis and single-carbon transfers are well known, there is very little information on the manner in which these two chemically dissimilar vitamins affect each other. We wish to make a preliminary report of observations which show that the administration of vitamin B12 causes a rise in the serum folic acid - level in patients with nutritional macrocytic anæmia.

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Authors and Affiliations

  1. Pathology Department, Government Headquarters Hospital, Trichinopoly, South India

    M. S. NARAYANAN

  2. Research and Control Division, Raptakos, Brett and Co., Private, Ltd., Worli, Bombay

    K. G. SHENOY & G. B. RAMASARMA

Authors
  1. M. S. NARAYANAN
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  2. K. G. SHENOY
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  3. G. B. RAMASARMA
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NARAYANAN, M., SHENOY, K. & RAMASARMA, G. Rise of Serum Folic Acid - Levels after Injection of Vitamin B12 in Nutritional Macrocytic Anæmia. Nature 178, 1347–1348 (1956). https://doi.org/10.1038/1781347a0

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  • DOI: https://doi.org/10.1038/1781347a0

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