Abstract
FOR the isolated, short-circuited frog skin with Ringer solution on both sides, it has been found that the active transport of sodium is equal to the current required to reduce the potential difference across the skin to zero1,2. It is also a well-known fact that the active transport of sodium depends on the oxygen supply to the skin. Francis and Pumphrey3 found that oxygen-free Ringer solution caused an irreversible disappearance of the potential difference across the skin in the course of 20–40 min.
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References
Ussing, H., and Zerahn, K., Acta Physiol. Scand., 23, 110 (1951).
Linderholm, H., Acta Physiol. Scand., 27, Supp. 97 (1952).
Francis, W. L., and Pumphrey, R. J., J. Exp. Biol., 10, 379 (1933).
Krogh, A., Indust. Eng. Chem. Anal. Edit., 7, 131 (1935).
Stapp, P., Proc. Soc. Exp. Biol. (N.Y.), 382, 46 (1941).
Conway, E. J., Science, 113, 270 (1951).
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ZERAHN, K. Oxygen Consumption and Active Transport of Sodium in the Isolated, Short-circuited Frog Skin. Nature 177, 937–938 (1956). https://doi.org/10.1038/177937a0
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DOI: https://doi.org/10.1038/177937a0
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